With some serious cardiovascular and psychiatric problems - including sudden death - related to these drugs, the FDA has mandated warning labels and patient guides. What a scary position for the parents who are using these drugs with their children. I am so glad that the strongest thing we have Dorothy on is Singular, which seems fairly safe. We have been so blessed to have found other very effective ways to deal with her issues, rather than to over-medicate her. My heart goes out to anyone who has to deal with the fear and/or heartache that these side effects cause.